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Reclaiming UC Symptom Relief May Be Possible

XELJANZ has helped some people with moderate to severe UC achieve remission at 8 weeks and stay in remission at 1 year.

XELJANZ is used to treat adults with moderately to severely active ulcerative colitis when 1 or more TNF blocker medicines have been used, and did not work well or cannot be tolerated.

XELJANZ is a pill, not an injection or infusion
pill in hand

Results From UC Clinical Trials* Prove XELJANZ Can Help Provide:

DISEASE

REMISSION

at 8 weeks

XELJANZ can help some patients achieve remission at 8 weeks.

STEROID-FREE

REMISSION

at 1 year

XELJANZ can help provide lasting, steroid-free remission in some patients at 1 year.

SYMPTOM

REDUCTION

in 2 weeks

XELJANZ can help reduce symptoms of rectal bleeding and stool frequency in some patients in as early as 2 weeks.

Adult patients with moderately to severely active UC were evaluated in clinical trials. Some patients in the clinical studies were taking background medicines and some were not. All patients in the studies had tried other medicines such as corticosteroids, azathioprine, or TNF blockers that did not work well or could not be tolerated. XELJANZ is approved for use in patients when TNF blockers did not work well or could not be tolerated.

Explore Clinical Trial Results

How XELJANZ Works

XELJANZ is a Janus kinase (JAK) inhibitor that helps regulate an overactive immune system. It helps disrupt JAK pathways from inside the cells, which are believed to play a role in inflammation.

Molecule graphic

These images of potential disease symptoms are for illustrative purposes only and are not intended to be fully anatomically accurate.

Discussing UC

No matter how long you’ve had UC, talking about it can feel awkward and embarrassing, even when the conversation is with your gastroenterologist (GI). Don’t hold back. Your GI is prepared for conversations like these. It's important that you have an open and honest discussion about your UC symptoms. Every appointment is an opportunity to improve the dialogue with your GI and discuss how to manage your UC.

Ready to make an appointment? Find A Healthcare Provider near you.

Prepare

Write down any questions or concerns you have ahead of your appointment. This can help make the conversation easier and give your doctor a more complete picture of your symptoms.

Share

When you’re with your GI or another member of your healthcare team, you may feel uncomfortable talking, but it’s important that you share. The information you share with your doctor could be helpful in finding a treatment plan that may work best for you.

Align

Communicate with your healthcare team to help them understand your goals, concerns, and expectations. This conversation will be useful in getting everyone on the same page.

View Doctor Discussion Guide

XELJANZ (tofacitinib) resource support brochures

Discover Support Resources

Whether you want to learn more about XELJANZ or have already been prescribed it for your moderate to severe UC, we can provide you with tools and support resources. We'll start by sending you a Welcome Kit in the mail and follow up with additional communications containing timely information and lifestyle tips.

Sign Up Now

Share Your Story

Share your story and help other adults learn about your experiences with moderate to severe UC and XELJANZ. Learning about your experience may be helpful for patients who are considering treatment or have already started.

Share Your Story

If selected, your story may appear on XELJANZ.com and/or in other marketing materials.

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